B.Pharm (II Semester) Pharmaceutical Organic Chemistrty-I
Multiple
choice Questions(MCQ)
1.
One of the
following is an example for alicyclic compound
A) Cyclohexane B) Toluene C)
Pyridine D) Furan
2. The
International Union of Pure and
Applied Chemistry was formed in the year
A) 1955 B) 1957 C) 1958 D)
1959
3. The
identical groups are present on
opposite sides is called as
A)
Dextro isomer B) Cis
isomer C) Trans isomer D) Optical isomer
4.
The General Formula for
alkane is
A) CnH2n B)
CnH2n
+ 2 C)
CnH2n
- 2 D) CnH2n + 1
5. The
type of hybridization occurs in alkene is
A) SP B)
SP3 C) SP2 D)
All the above
6. Hydrolysis
of Grignard reagent produce
A) Alkyl halide B) Alkyne C) Alkene D) Alkane
7. Relative
reactivities of alkyl halide in elimination reaction in the following order
A) RI>RBr>RCL>RF
B) RBr>RCl>RF>RI C) RCl>RF>RI>RBr D) RF>RI>RBr>RCl
8. “If more than one alkene can be formed by an
elimination reaction, the more stable alkene
product predominates” is known as
A) Hoffman
rule B) Saytzeffs rule C) Markovnikov’s rule D)Anti-Markovnikov’s rule
9. 1,3-Butadiene reacts with
ethylene is known as
A) Electrophilic addition B) Free radical substitution C) Diels-Alder Reaction D) Ozonolysis
10.
Pyrolysis of Ethane produce
A) Ethylene B)
Methane C) Hydrogen D)
All the above
11.
The following
substitution reaction is mainly occurs in alkyl halides
A)
Electrophilic B) Nucleophilic C) Free radical D) All the above
12.
The most stable carbocation is
A) Methyl B) Primary C) Secondary D)
Tertiary
13.
Chloroform is mainly used as
A) Refrigerant B) Anaesthetic C) cleansing agent in fire
extinguishers D) Solvent
14.
The _______ alcohol is
obtained by treating a Grignard reagent with formaldehyde
A) Tertiary B) Secondary C)
Primary D)
All the above
15.
The most acidic alcohol is
A) Aromatic B)
Primary C) Secondary D) Tertiary
16.
Aldehydes with α-hydrogens
undergo self-addition in the presence of a base is known as
A) Cannizzaro Reaction B) Benzoin condensation C) Perkin reaction D) Aldol Condensation
17.
4-Hydroxy, 3-methoxy benzaldehyde is known
as
A) Vanillin B) Cinnamaldehyde C) Paraldehyde D) Hexamine
18.
Which
of the following compound is most acidic
A)
Chloroacetic acid B) Dichloroacetic acid C) Trichloroacetic
acid D) Acetic acid
19.
One of the following is not an acid derivative
A) Anhydride B) Grignard reagent
C) Acid chloride
D) Amide
20. The
presence of electron releasing group in amines ___________ basicity
A) Some group increase or decrease B) No change in C)
Decreases D) Increases
21.
One of the
following is an example for heterocyclic compound
A) Cyclohexane B) Toluene C)
n-propylamine D) Furan
22.
The International Union of Pure and Applied Chemistry was established in the year
A) 1955 B) 1957 C) 1958 D)
1959
23.
The IUPAC Nomenclature the compound
is
A) 2-Hydroxy-4-methylpentanoicacid B) 4-Hydroxy-2-methylpentanoicacid
C) 4-Carboxy-4-methyl 2-butanol D) 1-Carboxy-2-methyl 4-pentanol
24.
The General Formula for
alkene is
A) CnH2n + 2 B) CnH2n - 2 C) CnH2n D) CnH2n + 1
25.
The type of hybridization occurs in alkane
is
A) SP3 B) SP2 C)
SP D) All the above
26.
E1 mechanism is
A) Uni molecular B) Two steps C) more
favour for 3o Alkyl halide D) All
the above
27.
Relative reactivities of
alkyl halide in elimination reaction in the following order
A)RBr>RCl>RF>RI B) RI>RBr>RCl>RF C) RCl>RF>RI>RBr D) RF>RI>RBr>RCl
28.
“If more than one alkene
can be formed by an elimination reaction, the more stable alkene
product predominates” is
known as
A) Hoffman
rule B) Markovnikov’s rule C) Saytzeffs rule D)Anti-Markovnikov’s rule
29.
Wurtz Synthesis is used for the preparation of
A) Alkanes B) Alkenes C) Alkyl halide D)
Alkynes
30.
Free radical substitution of methane produce
A) Methyl chloride B) Methylene chloride C)
Chloroform D) All the above
31. The
higher reactivity of an alkene or alkyne, as compared to an alkane, is due to
A)
sigma bonds B) Pi bonds C) hydrogen bonds D) None of these
32. Two
isomeric forms of a saturated hydrocarbon have
A) Same structure B)
different compositions of elements.
C) Same molecular formula D)
different content of hydrogen isotopes.
33. A Chlorination of alkanes is an
example of________ reaction.
A)Radical B) Free radical C)
elimination D) addition
34. A homologous series is a series of compounds in which
34. A homologous series is a series of compounds in which
A) Adjacent members differ by a CH2
unit. B) Have same functional group
C) general molecular formula D) All the above
35. The presence of electron-releasing alkyl
groups in carboxylic acid--------------- the acidity
A) Increase B) Decrease C)
Neutralize D) No change in
36 As per IUPAC, which of the following functional
group is a principle functional group
A) Amide B) Aldehyde C) Ketone D)
Carboxylic acid
37. The oxidation of secondary alcohol produce
A) Aldehyde B) Ketone C) Primary alcohol D) All
the above
38.
The higher reactivity of an alkene or
alkyne, as compared to an alkane, is due to
A)
sigma bonds B) Pi bonds C) hydrogen bonds D) None of these
39.
Two isomeric forms of a saturated
hydrocarbon have
A) Same structure B)
different compositions of elements.
C) Same molecular formula D)
different content of hydrogen isotopes.
40.
A Chlorination
of alkanes is an example of________ reaction.
A)Radical
B) Free radical C)
elimination D) addition
41.
A homologous series is a series of
compounds in which
A)
Adjacent members differ by a CH2
unit. B) Have same functional group
C) general molecular formula D) All the above
42.
Alkanes which have two methyl groups
attached to the second last carbon atom of the continuous chain is prefixed as
A)
Neo B)
Iso C) n- D) None of the above
43.
As per IUPAC,
which of the following functional group is a principle functional group
A) Amide B) Aldehyde C) Ketone D) Carboxylic
acid
44.
The shape of SP2
hybridized orbital is
A) Triangle B) Linear C) Tetrahedral D) None of the above
45.
The higher The Order of
reactivity of alkyl halides in E2 reaction is
A)
3o >2o >1o B) 3o <2o <1o C) 2o >3o
>1o D) 1o
>3o >2o
46.
The hydroxyl group is
attached to an unsaturated carbon atom is called as
A)
Alcohols B) Enols C) Phenols D) carbinols
47.
Primary alcohols are obtained by treating a
Grignard reagent with
A)
Formaldehyde B) Acetaldehyde C) Acetone D)
All the above
48.
Ozonolysis of 2-butene produces
A)
Acetaldehyde + Acetone B) 2
moles of acetaldehyde
C)
2 moles of acetone D)
Acetone + Etanol
49. A temporary polarization between atoms in a
multiple bond in the presence of an attacking reagent
A)
Electromeric effect B) Resonance
effect C) Dipole moment D)Polar effect
50.
Oxime is formed by the reaction of carbonyl
group with
A)
Hydroxylamine B) Hydrazine C)
Phenyl hydrazine D) Semicarbazide
51.
The presence of electron-releasing alkyl
groups in carboxylic acid--------------- the acidity
A)
Increase B) Decrease C) Neutralize D) No change in
52.
Hydrolysis of ester produce
A)
Two moles of acid B) Two moles of
alcohol C)
Acid + Amine D) Acid + Alcohol
