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Professor & HoD Department of Pharmaceutical Chemistry, JSS College of Pharmacy, (Constituent College, JSS Academy of Higher Education &Research-Deemed to be University, Mysuru) Ooty-643 001, The Nilgiris, Tamilnadu,INDIA The author has about 23 years of teaching and research experience. The Author has more than 110 research publications in reputed National and International journals and has H-index 16 by scopus. He has also published 9 books. He is a recognized research guide for Ph.D in JSS Academy of Health Education and Research and He served as editorial member and reviewer in many reputed National and International journals. He is the winner in Drug Discovery Hackathon-2020 for Covid-19 Drug discovery organized by Govt of India and also received a Research grant of 14.35 lakhs in phase-II research. He is nominated as BOS member in various universities. He has organized many national and International seminar/ workshop/ Conferences etc sponsored by various funding agencies.

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Friday, March 29, 2019

Pharm.D_POC_Allcyclic Compounds & Dienes_MCQ

Pharm.D_POC_Allcyclic Compounds & Dienes_MCQ

1.The angle strain in cyclobutane is
A) 24°44’   
B) 29°16’
C) 19°22’   
D) 9°44’

2.Identify the incorrect statement regarding cycloalkanes                                             
a) These have sp3 hybridized carbons                                                                                 
b) These have tetrahedral bond angles                                                                                 
c) Stability of cycloalkanes varies directly with their respective size                                                      d) These undergo nucleophilic substitution reactions

3. Identify the compound with the highest ring strain                                                           
a) Cyclohexane                                                                                                                             
b) Cyclopropane                                                                                                                             
c) Cyclopentane                                                                                                                                 
d) Cyclobutane

4.A cycloalkane with 10 carbons will have _____ hydrogen atoms                                 
a) 10                                                                                                                                                          b) 18                                                                                                                                                          c) 20                                                                                                                                                   
d) 22

5.Cycloalkanes are associated with the general formula                                                   
a) CnH2n+2                                                                                                                                            b) CnH2(n+2)                                                                                                                                     
c) CnH2n+1-r                                                                                                           
d)CnH2(n+1-r)

6.What is the normal tetrahedral bond angle
a) 109°
b) 107°
c) 109.5°
d) 107.5°

7.Which of the following cyclohexane undergos ring opening cum addition
a) Cyclopropane
b) Cyclopentane
c) Cyclohexane
d) Cycloheptane

8.What is the angle of strain in cyclopropane
a) 24°04'
b) 24°14'
c) 24°24'
d)24°44'

9.What is the angle of strain in cyclobutane
a) 9°24'
b) 9°34'
c) 9°44'
d) 9°54'

10.Which among the following is the most stable form of cyclohexane
a) Chair
b) Boat
c) Twisted chair
d) Twisted boat

11.How do we convert benzene to cyclohexane                                                                      
a) Wurtz reaction 
b) Clemmensen reduction
c) Simmons Smith reaction 
d) Catalytic reduction  

12.What is the angle of strain in cyclohexane
a) 5°44'
b) -5°44'
c) 5°16' 
d)- 5°16'

13.Which among the following dienes undergo addition with the help of radical-chain mechanism?     a) Cumulated dienes                                                                                                                         
b) isolated dienes                                                                                                                             
c) simple dienes                                                                                                                                 
d) Conjugated dienes

14.Identify the statement which is related to Diels-Alder reaction
a) It is very stereospecific
b) Molecular distortion takes place
c) Cyclic dienes react very slow than the linear chain dienes
d) Addition of maleic anhydride to cyclopentadiene causes diene and dienophile to produce different product

15.How many sigma bonds are there in 1,3 -butadiene?                                                         
a) 3                                                                                                                                                            b) 6                                                                                                                                                            c) 9                                                                                                                                                         
d) 12

16.1,3-butadiene is                                                                                                                                  a) a planar compound                                                                                                                      
b) a cumulated diene                                                                                                                        
c) an isolated diene                                                                                                                                
d) a conjugated diene

17.Which diene is the most stable
a) Isolated diene
b) Cumulated diene
c) Conjugated diene
d) Vicinal diene

18.Dienes preferably undergo 
a) Substitution 
b) Elimination  
c) Addition 
d) Cyclisation  

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